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Vitamin K occurs in two natural forms, vitamin K1 (phylloquinone) produced by plants, and vitamin K2 (menaquinone) produced by intestinal bacteria

Setria is a registered trademark of Kyowa Hakko Bio Co., LTD

[DOI] [PubMed] [Google Scholar] Jones D.P., Moldus P., Stead A.H., Ornstad K., Jrnvall H., Orrenius S

This topic is another analytical challenge by itself, especially since the quantification process requires not only establishing the whole content of the peptide in the sample (using, e.g., amino acid analysis, with TLC, HPLC, GC-MS, LCMS, CE, or RMN methods) but also the content of the counterion (using either LC or GC methodologies), water/humidity content (using Karl Fischer), and impurities tests for the evaluation of residual solvents (such as ACN, DMF, DCM through GC-HS-MS), heavy metals, and peptide-related and nonrelated impurities

Am J Physiol Endocrinol Metab 2010

however, the amount of cholesterol in the HDL pool (HDL-C) and the number and quality of HDL particles (HDL-P) are independent concepts that are important to consider in the context of HDL function